AN NMR STUDY ON THE CLPC OPERON BINDING REGION OF TRANSCRIPTION FACTOR CTSR FROM BACILLUS SUBTILIS


C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells

Abstract Background Triptolide is a structurally unique diterpene triepoxide with potent antitumor activity.However,the effect Scissor and mechanism of triptolide on hepatocellular carcinoma (HCC) is not well studied.Methods Cells were treated with triptolide, and the anti-HCC activity of triptolide was evaluated using flow cytometry, western blot,

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Role of Lipid-Based and Polymer-Based Non-Viral Vectors in Nucleic Acid Delivery for Next-Generation Gene Therapy

The field of gene therapy has experienced an insurgence of attention for its widespread ability to regulate gene expression by targeting genomic DNA, messenger RNA, microRNA, and short-interfering RNA for treating malignant and non-malignant disorders.Numerous nucleic acid analogs have been developed to Lipo 6 target coding or non-coding sequences

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Experimental Study on the Effects of Controllable Parameters on the Healthy Operation of SF-2A Material Water-Lubricated Stern Bearing in Multi-Point Ultra-Long Shaft Systems of Ships

Effective control of the health operating condition of multi-support, ultra-long shaft system water-lubricated stern bearings is crucial for supporting the intelligent maintenance and health management of ships.This study investigates the failure modes of water-lubricated stern bearings and focuses on the critical failure modes of abnormal wear and

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